Magnetic Resonance Elastography in Infants
Not Applicable
Terminated
- Conditions
- Liver Disease
- Registration Number
- NCT02201472
- Lead Sponsor
- Children's Hospital Medical Center, Cincinnati
- Brief Summary
MRI \& MRE in infants
- Detailed Description
The purpose of the present pilot study is to determine the feasibility of using MRI and MRE to evaluate the liver in infants with suspected liver disease.
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 2
Inclusion Criteria
- Infants < 6 months of age
- Known liver disease based (liver enzymes, bilirubin, and/or GGT at least twice the upper limit of normal for age)
- Parental/LAR permission obtained
Exclusion Criteria
- Standard MRI exclusion criteria as set forth by the CCHMC Division of Radiology
- Severe coagulopathy (INR > 3 or platelets <50,000)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Feasibility of MRE to Provide Evaluable Images That Illustrate the Stiffness of Liver Parenchyma in an Infant Population 12 months To determine the feasibility of MRE to provide evaluable images that illustrate the stiffness of liver parenchyma in an infant population.
- Secondary Outcome Measures
Name Time Method