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Clinical Trials/NCT06345664
NCT06345664
Recruiting
N/A

Interdisciplinary, E-health Based, Multimodal Follow-up of Somatic, Sleep-related and Psychological Symptoms of Very Immature Preterm Born Babies in Different Age Groups for the Further Development of Previous Care Structures

University Hospital Tuebingen1 site in 1 country90 target enrollmentMarch 1, 2023
ConditionsPreterm Birth

Overview

Phase
N/A
Intervention
Not specified
Conditions
Preterm Birth
Sponsor
University Hospital Tuebingen
Enrollment
90
Locations
1
Primary Endpoint
Youth Self Report (YSR)
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

The aim of the study is to assess mental and somatic symptoms of preterm born children at the ages of 2, 5 and 10 by a multidisciplinary team and to evaluate an app that screens for these symptoms. Furthermore, there will be an evaluation of an intervention by our multidisciplinary team that provides recommendations for further treatment and diagnostic procedures of the children.

Detailed Description

* At first, there will be focus groups with experts and affected families to finalize and optimize the study procedure. After that, 90 children will be recruited (ages 2, 5 and 10) * T0: App-questions for the children at the ages of 5 and 10 and the parents of all children to mental, somatic and sleep problems of the children and well-being of the parents, sleep tracking and recording of a sleep sequence of the children; differentiated examinations and questionnaires to mental and somatic problems of the children by interdisciplinary study team * Interdisciplinary study team meeting to generate recommendations for the families * Interdisciplinary study team recommendations for the families * T1: Comparable to T0 but only measurements that were assessed with questionnaires/at home plus post-experimental questionnaire * Focus groups with participating families and the study team experts for evaluation of the study procedure and intervention

Registry
clinicaltrials.gov
Start Date
March 1, 2023
End Date
May 2025
Last Updated
last year
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

PD Dr. Annette Conzelmann

Principal Investigator

University Hospital Tuebingen

Eligibility Criteria

Inclusion Criteria

  • female and male preterm born children (\<32 week of pregnancy) that are treated at the clinic in Tübingen and their parents
  • Existence of systematical neonatal data and consent of the care person to use this data
  • Existence of the data of the 2 year regular follow-up (for the 5 and 10 year olds)

Exclusion Criteria

  • lack of access to a mobile phone/tablet including internet access
  • insufficient knowledge of the German language of both parents

Outcomes

Primary Outcomes

Youth Self Report (YSR)

Time Frame: Baseline and 36-38 weeks after baseline

Screening for mental illness

Bayley Scales of Infant and Toddler Development

Time Frame: Baseline

IQ testing

Sleep Self Report (SSR)

Time Frame: Baseline and 36-38 weeks after baseline

Screening of sleeping behaviour

Child Behavior Checklist (CBCL)

Time Frame: Baseline and 36-38 weeks after baseline

Screening for mental illness

Parent's Stress Inventory (EBI)

Time Frame: Baseline and 36-38 weeks after baseline

Load as parents and relationship to the child

KIDSCREEN-27 (The KIDSCREEN)

Time Frame: Baseline and 36-38 weeks after baseline

Health related quality of life

Wechsler Intelligence Scale for Children (WISC-V)

Time Frame: Baseline

IQ testing

Somatics

Time Frame: Baseline and 36-38 weeks after baseline

Questions to somatic symptoms (diagnoses, inpatient stays, medication, early support) physical therapy, hearing impairment or visual disturbance, pulmonary symptoms, seizure disorders, health related quality of life, body weight, size)

App-questions

Time Frame: Baseline and 36-38 weeks after baseline

Questions reflecting the questionnaires

Children's Sleep Habit Questionnaire (CSHQ-DE 4-10)

Time Frame: Baseline and 36-38 weeks after baseline

Screening of sleeping behaviour

Diagnostic-system for mental illness for children and adolescents - III (DISYPS-III SCREEN FBB and SBB)

Time Frame: Baseline and 36-38 weeks after baseline

Screening for mental illness

Postexperimental questionnaire

Time Frame: 36-38 weeks after baseline

Evaluation of the study

Secondary Outcomes

  • Actigraphy measurement(Baseline)
  • Sleep cartoon for children(Baseline and 36-38 weeks after baseline)
  • Video of a sleeping sequence(Baseline)
  • Demographic data(Baseline)
  • Kiddie-Sads-Present and Lifetime Version (K-SADS PL)(Baseline)
  • Self efficacy dealing with social situations (WIRKSOZ)(Baseline and 36-38 weeks after baseline)
  • Group interviews(Baseline and 36-38 weeks after baseline)

Study Sites (1)

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