Preventing Relapse After Successful Electroconvulsive therapy (ECT) for Depression: A randomized controlled trial on lithium as add-on to personalized maintenance ECT

• Conditions: depression; mood disorder; 10027946

• Registration Number: NL-OMON49873
• Lead Sponsor: niversiteit Antwerpen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 24

Inclusion Criteria

- Major depressive disorder patients
- Treatment with either an adequately dosed TCA (with therapeutic blood levels)
or venlafaxine (target dose of >= 225mg/day)
- Remitted (IDS-C<=12) after an acute course of ECT
- Age 18 or older

Exclusion Criteria

- Patients with bipolar disorder, schizoaffective disorder or schizophrenia
- Patients already treated with Lithium, or with a contra-indication for
Lithium use
- Patients with documented dementia or intellectual disability
- Substance abuse or dependence in the past 6 months

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Improvement of prevention of relapse by 20%</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>n.a.</p><br>