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Effects of Mucoprotective Product on Xerostomia

Phase 4
Completed
Conditions
Xerostomia
Interventions
Other: XER2020
Registration Number
NCT01316393
Lead Sponsor
Camurus AB
Brief Summary

In the present study with a randomized, cross-over, blind, placebo controlled design, the effects of a salivary substitute product and a new mucoprotective product with similar mechanisms of action but with different composition and characteristics will be evaluated in cancer patients suffering from xerostomia.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
20
Inclusion Criteria
  1. The patient must be at least 18 years of age.
  2. The patient must have clinical symptoms of xerostomia (dry mouth) due to treatment of head and neck cancer
  3. The patient must understand and consent in writing to the procedure.
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Exclusion Criteria
  1. Do not meet the criterion for "dry mouth" regarding saliva secretion threshold values.
  2. Known allergy to ingredients in the products to be used in the trial and/or allergy to soy, peanuts, citrus fruit,Yerba Santa or methyl parabene
  3. Patients who are unable or unwilling to cooperate with study procedures.
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Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Arm && Interventions
GroupInterventionDescription
XER2020XER2020mucoprotective product
XER2020 placeboXER2020-
Saliva NaturaXER2020salivary substitute
Primary Outcome Measures
NameTimeMethod
OHIP questionaire health impact profile7 days

Effect on oral health quality will be assessed after each treatment period

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Department of Prosthetic Dentistry, Malmö University

🇸🇪

Malmö, Sweden

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