MANAGEMENT OF PSORIASIS WITH AYURVEDA FORMULATION

Phase 1

Completed

• Conditions: Diseases of the skin and subcutaneous tissue,

• Registration Number: CTRI/2018/12/016594
• Lead Sponsor: J S AYURVED MAHAVIDYALAYA

Brief Summary

This is randomized prospective interventional clinical study performed at P.D. Patel Ayurveda hospital, Nadiad, Gujrat. Total 37 patients were registered among them 30 patients were completed the treatment and 7 patients discontinued the treatment. 30 patients were equally divided in 2 group through computer generated block randomize method, 15 patients in each group. All the patients were treated with following schedule: Patients of group A were treated with lelÄ«taka mÄká¹£ika yoga tablet has given 2 tablets twice in a day meal for 8 weeks. Patients of group B were treated with kaiÅ›ora guggulu has given 3 tablets thrice in a day and mañjiṣṭhÄdi kvÄtha has given 40 ml twice in a day at empty stomach. Patients were assessed by grade score symptomatically before and after completion of treatment. PASI was calculated with online calculator. DLQI was assessed with questionnaire.  The study result was statistically analyzed by using the un-paired ‘t’ test. A value of p<0.05 was considered as statistically significant.  LelÄ«taka-mÄká¹£ika yoga was take easily by every patient. Both medications are useful in dermatological disorders. LelÄ«taka-mÄká¹£ika yoga vaá¹­i is more effective in compared kaiÅ›ora guggulu and mañjiṣṭhÄdi kvÄtha.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-12-15
• Last Update Posted: 2020-05-24

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Asvedana (loss of perspiration) 2.
• Mahavastu / Mandala (lesions distibution) 3.
• Matsyasakalopama (Scaling) 4.
• Krsna aruna varna / Abhrakpatrasama (Discoloration) 5.
• Kandu (Itching) 6.
• Ruksata (Dryness) Following any one of this sign 1.
• Auspitz,s sign 2.
• Candle grease sign 3.
• Koebner,s phenomenon.

Exclusion Criteria

• Female patients have pregnancy or lactating period.
• Patient with associated disease like cardiovascular disorders, hyperthyroidism or hypothyroidism, cancer, tuberculosis, heart diseases, psoriatic arthritis, kidney and liver disorders.
• Patients having HbA1c above 7.5 of diabetes mellitus.
• Patients who have taken medication of corticosteroids, drugs within last 6 months.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
CHANGES IN SIGNS AND SYMPTOMS OF PSORIASIS	8 WEEKS

Secondary Outcome Measures

Name	Time	Method
PSORIASIS AREA AND SEVERITY INDEX	DERMATOLOGY QUALITY LIFE INDEX

Trial Locations

Locations (1)

P D Patel Ayurveda Hospital; 🇮🇳 Kheda, GUJARAT, India

P D Patel Ayurveda Hospital

🇮🇳Kheda, GUJARAT, India

Dr Vigna R Vyas

Principal investigator

8469908928

vignavyas777@gmail.com