NCT02570763
Withdrawn
N/A
Combining Non-Invasive Brain Stimulation With Cognitive Behavioral Intervention in Substance Use Disorder
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Active tDCS
- Sponsor
- University of Minnesota
- Primary Endpoint
- Therapy Content Memory Assessment
- Status
- Withdrawn
- Last Updated
- 8 years ago
Overview
Brief Summary
The current study aims to examine the safety and feasibility of utilizing tDCS to enhance affect-laden episodic memory consolidation among adults with co-occurring alcohol use and anxiety disorders who have recently undergone detoxification as a step toward the translational clinical application of this approach.
Investigators
Eligibility Criteria
Inclusion Criteria
- •DSM IV diagnosis of panic disorder (with or without agoraphobia), generalized anxiety disorder, or social anxiety disorder within the past 30 days
- •DSM IV diagnosis of alcohol dependence within the last 30 days
- •inpatient treatment at Lodging Plus primarily for alcohol (vs. other drug) dependence
- •alcohol use in the 30 days preceding the study
- •willingness to provide informed consent
- •minimum of a sixth grade English reading level (deemed necessary to complete study materials); as determined by their being able to read and understand the consent form.
- •Living within reasonable driving distance (1 hour or less) of the Twin Cities to allow for in-person follow-up interviews
Exclusion Criteria
- •lifetime history of psychosis or mania by history.
- •cognitive (e.g., dementia) or physical impairment (e.g., blindness) that interferes with study participation report or as judged by PI/study physician.
- •Current suicide risk as deemed by the PI and study physician to be serious and ongoing
- •any medical condition or treatment with neurological sequelae (e.g., stroke, tumor, loss of consciousness of more than 30 minutes, HIV, seizures)
- •history of ECT
- •document loss of consciousness (LOC) for longer than 30 minutes or LOC with neurological sequelae
- •pregnancy
- •Although seizures are not a known risk of tDCS intervention (Fregni et al., 2006; Nitsche et al., 2008), anyone with a history or a risk for seizures will be excluded from the study
- •anyone with metal objects implanted in their head or neck
- •anyone taking stimulant medications for any reason as we wish to avoid two sorces of neurostimulation
Outcomes
Primary Outcomes
Therapy Content Memory Assessment
Time Frame: 24 hours
Participant's will complete daily assessments of their memory for therapy content from the previous session.
Similar Trials
Completed
N/A
Investigating Non-invasive Brain Stimulation to Enhance Fluency in People Who StutterStuttering, DevelopmentalNCT03335722University of Oxford43
Completed
N/A
Cognitive Enhancement in Depression (The COG-D Study)AgingDepressionCognitive SymptomNCT05400512Vanderbilt University Medical Center16
Completed
N/A
Effect of a Non-Invasive Brain Stimulation Technique on Smoking Cessation BehaviorsTobacco Use DisorderNCT03386253University of Minnesota16
Completed
N/A
Brain Stimulation, Clinical Symptoms and CognitionSchizophreniaNCT05053451University of California, Davis5
Unknown
Phase 2
Non-invasive Brain Stimulation for the Treatment of Psychiatric DisordersMental DisordersNCT01872143Federico II University100