The effect of thyrophyte herbal composition on the weight of patients with primary hypothyroidism
Phase 2
- Conditions
- Hypothyroidy.Ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere(E00-E90)
- Registration Number
- IRCT20210101049909N1
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Age: 20 to 65 years
Patients known to have primary hypothyroidism by an endocrinologist
Hypothyroid patients with overweight or obesity whose weight has not been controlled with levothyroxine
Exclusion Criteria
Uncontrolled systemic diseases
Any diet for weight loss during the study and 3 months before arrival
Take a vitamin supplement at least three months before or during the study
Patient dissatisfaction with continued cooperation
Pregnancy
Lactation
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Weight. Timepoint: Before and after intervention. Method of measurement: To measure weight, calculate the ratio of weight in kilograms to height squared in meters (body mass index) and calculate the ratio of waist to hip in centimeters (WHR) using weight and tape meters.
- Secondary Outcome Measures
Name Time Method ipid profile. Timepoint: Before and after intervention. Method of measurement: By blood test in mg/dl.;Fasting blood sugar. Timepoint: Before and after intervention. Method of measurement: By blood test in mg/dl.;Thyroid hormone (TSH, FT4, T3). Timepoint: Before and after intervention. Method of measurement: By blood test in ng/dl.;Depression score on Beck Depression questionnaire. Timepoint: Before and after intervention. Method of measurement: Beck Depression questionnaire.;Quality of Life score on WHO Quality of Life Questionnaire. Timepoint: Before and after intervention. Method of measurement: WHO Quality of Life Questionnaire.