Ionized Hypocalcemia as a Prognostic Factor of Early Mortality inTraumatic Brain Injury

Phase 1

• Conditions: Injury, Occupational Diseases, Poisoning; Nervous System Diseases; Intensive care unit

• Registration Number: PACTR202204664745348
• Lead Sponsor: Faculty of Medicine Ain Shams University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-04-13
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1- Patients aged more than or equal 18 years old.
2- Patients of both sexes.
3- Patients admitted to hospital with traumatic brain injury.

Exclusion Criteria

1. Refusal of nearest relative to sign the written concept for study participation.
2. TBI older than 24 hours.
3. Diseases or medications affecting calcium metabolism such as hyperparathyroidism, acute pancreatitis and treatment with hydrochlorothiazide.
4. Recent history of hyperphosphatemia (>1.32 mmol/L) or hypomagnesemia (0.61 mmol/l).

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mortality rate in patients with traumatic brain injury with ionized hypocalcemia

Secondary Outcome Measures

Name	Time	Method
eurological deficit or any organ dysfunction