Expression of factors involved in bile acid metabolism throughout the gastrointestinal tract Amendement: Expression of HIF-1alpha protein in upper GI tractus

Recruiting

• Conditions: indirect Crohn's Disease; no direct abberations are invistigated; 10018012

• Registration Number: NL-OMON33749
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 50

Inclusion Criteria

Subjects undergoing double balloon enteroscopy

Exclusion Criteria

Uncorrected coagulopathy at moment of enteroscopy. Subjects that do not fully understand the patient information folder (p.e due to insufficient comprehension of Dutch language)

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>To obtain insight in the expression of several nuclear receptors across the<br /><br>entire human gastrointestinal tract.<br /><br><br /><br>Amendement: To obtain insight in the expression and amount of HIF-1 alpha in<br /><br>normal tissue of upper gastrointestinal tract</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Possible association between nuclear receptors and pathologic diagnosis (i.e.<br /><br>Crohn*s disease)</p><br>