utritional needs and physical function in community dwelling geriatric outpatients to counteract sarcopenia and ultimately preserve daily functio
Completed
- Conditions
- Sarcopenia10028302low muscle mass1000301810028037
- Registration Number
- NL-OMON42139
- Lead Sponsor
- Vrije Universiteit Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 270
Inclusion Criteria
Geriatric outpatients: Elderly referred to the geriatric outpatient clinic of the Center of Geriatric Medicine Amsterdam (COGA), VU University Medical Center Amsterdam.;Healthy age matched controls: Elderly attending social or group activitties, being medically stable, free from major diseases.
Exclusion Criteria
Geriatric outpatients: No exclusion criteria will be applied.;Healthy age matched controls: Exclusion criteria from the European MYOAGE study will be applied; dependent living status, the inability to walk a distance of 250 meter, morbidity, immobilization, the use of specific medication, orthopedic surgery , and participation in athletic events.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The primary study parameter is muscle mass on which the sample size calculation<br /><br>was made.<br /><br>- The correlation of muscle mass with the secondary study parameters in<br /><br>geriatric outpatients.<br /><br>- The difference in muscle mass between geriatric outpatients and healthy age<br /><br>matched controls. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Muscle-related parameters:<br /><br>- Muscle strength<br /><br>- Physical performance<br /><br>Energy expenditure:<br /><br>- Basal metabolic rate<br /><br>- Actual physical activity<br /><br>Nutritional status:<br /><br>- Energy intake<br /><br>- Protein status<br /><br>Cellular senescence:<br /><br>- Senescent cells</p><br>