Study on comparing drug response of dexmedetomidine and ketamine with fentanyl and morphine (drug name) for laparoscopic operatio
Phase 1
- Conditions
- Health Condition 1: K800- Calculus of gallbladder with acutecholecystitis
- Registration Number
- CTRI/2023/07/055452
- Lead Sponsor
- P Ramyadevi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
BMI: 18.5 â?? 24.9
ASA (American Society of Anaesthesiologists) physical status of I and II
Exclusion Criteria
Pregnant and Lactating Women
ASA physical status of III and IV
Significant pain related neurological conditions
Patients currently taking opioid
Patients with allergies to study medication
Patient Refusal
H/O Drug Abuse, Psychiatric disease
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mean systolic blood pressure between opioid free & opioid based anesthesia study groups for elective laparoscopic surgery.Timepoint: It will be monitored at baseline, before induction, post induction 3min, before intubation, post intubation 1 min, beginning of surgery, bef <br/ ><br>ore abdominal insufflation, post abdominal insufflation 3min, 15 min,30 min, 45 min, 60 min, 75 min, 90 min, 105 min, 120 min, 135 min & 150 min from induction , post deflation 3min, before extubation, after extubation 1min.
- Secondary Outcome Measures
Name Time Method To compare the use of Postoperative Rescue Analgesia & the use of rescue for Postoperative Nausea & Vomiting.Timepoint: Postoperative pain will be assessed by visual analog scale score at 2 hours, 4 hours, 6 hours, 8 hours, 12 hours, 16 hours, 20 hours, 24 hours.