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Aerobic Exercise on Fitness Score and Blood Glucose Level in Adolescents Girls With Diabetes Mellitus

Not Applicable
Completed
Conditions
Type 1 Diabetes Mellitus
Interventions
Other: aerobic exercise
Registration Number
NCT06139913
Lead Sponsor
MTI University
Brief Summary

In adolescent diabetic girls, a correct life style, including diet and physical activity, is part of a correct intervention protocol. Thus, the aim of this study was to evaluate the effects of aerobic training intervention, based on heart rate at glycemic level , on clinical and physiological parameters in adolescent girls with type 1 diabetes forty type1 DM girls will randomly assigned to an intervention (study group ) or control group. The study group will perform a supervised aerobic exercise training based on heart rate whereas control group maintained their usual lifestyle. Anthropometric fitness score measures, blood analysis will assess at baseline and after intervention.

Detailed Description

fourty adolescents girls were diagnosed by physician as having type 1 diabetes mellitus and recruited from outpatient internal of El-Hussien hospital in Egypt . girls ages were between 13 and 18yr old; . The following inclusion criteria was applied to all participants in the study : all girls had type 1DM for more than 3 years, Their dose of insulin intake over 0.4 U/Kg/day, Body mass index (BMI) between 25 and 30 kg/m2 . Moderate-intensity aerobic exercise was defined according to the classification standard of the ACSM, which refers to exercise where the HRR of subjects is 64-76%; the moderate-intensity target heart rate area was set in advance and controlled by heart rate monitor during the intervention, and the menarche was began from 3 to 5 years. The patients had no history of severe and frequent hypoglycemia in the last 6 months (\< 60 mg/dl, more than twice a week).

All participants attended a clinic for clinical assessments before and after treatment plane.

1. Body Mass Index (BMI)

2. Fitness score

3. Target Heart Rate

4. Fasting blood samples, post prandial and HbA1c: were taken for the following measurements: glucose.

5. Estradiol blood test

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
40
Inclusion Criteria
  • All girls had type 1DM for more than 3 years,
  • Their didn't of insulin intake over 0.4 U/Kg/day, Body mass index (BMI) between 25 and 30 kg/m2
Exclusion Criteria
  • Diabetes as a secondary condition
  • Any known cardiac defects and Macrovascular or microvascular chronical complications.
  • Insulin therapy and regulate dietary intake Were followed through diabetes physician.

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
aerobic exerciseaerobic exerciseaerobic exercise using treadmill
Primary Outcome Measures
NameTimeMethod
Fitness score:3 month

2- Fitness score: were assessed by multifrequency bioelectrical impedance analysis (MF-BIA; InBody 3.0, Biospace, Seoul, Korea)

Estradiol blood test3 month

Estradiol blood test of the participants was done by a laboratory assistant to evaluate the estrogen level of the participants' pre- and post-exercise intervention. The serum concentrations of estradiol (E2) were analyses were performed on day 3 after onset of menstruation

Fasting blood samples, post prandial and HbA1c:3 month

Fasting blood samples, post prandial and HbA1c: were taken for the following measurements: glucose.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

faculty of pysical therapy, MTI university

🇪🇬

Cairo, Egypt

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