Effects of Phyllanthus amblica in Non-erosive reflux disease
Phase 2
- Conditions
- on-erosive gastroesophageal reflux disease (NERD).Gastroesophageal reflux disease without esophagitis
- Registration Number
- IRCT2016061428469N1
- Lead Sponsor
- Vice chancellor for research,School of Traditional Medicine, Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 68
Inclusion Criteria
having the classic symptoms of reflux disease and normal endoscopy; patients with 16 to 80 years old; the normal examination by a gastroenterologist Exclusion criteria: erosive esophagitis in endoscopy; smoking; ongoing alcohol users; OB positive; risk of peptic ulcer or cancer; pregnant women; breast feeding women; any digestive disorder which requires new protocols; significant surgical or medical disorders clinically; hospitalization; use of PPI for 10 days ago; and use of H2 blocker for 2 weeks ago.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain or heartburn. Timepoint: At the begining, end of the Second week, end of the forth week. Method of measurement: Gastroesophageal reflux standard questionnaire.
- Secondary Outcome Measures
Name Time Method Acid regurgitasion /sour taste in the mouth. Timepoint: At the begining, end of the Second week, end of the forth week. Method of measurement: Gastroesophageal reflux standard questionnaire.