Evaluating Patient Knowledge About Perioperative Neurocognitive Disorders (KNOW-PND Study)
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- PND knowledge
研究概览
简要总结
Neurocognitive disorders remain one of the major perioperative complications. They are associated with delayed recovery, prolonged length of hospital stay and impacts on patients' quality of life. The incidence of PND ranges from 15-50%.
While several causes have been investigated, PND seems to be due to the non-resolution of an inflammatory cascade, making some patients more at risk than others. As such, major risk factors include old age and lower education levels.
As the global proportion of people aged 60 and above between 2015 and 2050 will increase from 12% to 22% and worldwide surgeries increases to >300 million procedures per annum the incidence of perioperative neurocognitive disorders with high morbidity and mortality will go up.
In 2015, the American Society of Anesthesiologists (ASA) launched the 'Perioperative Brain Health Initiative' to increase awareness about perioperative neurocognitive disorders. (PND) While physicians seems to be more and more aware about this condition, data regarding patient awareness are not available.
An observational, single-centre, cross-sectional survey study (with initially a feasibility study) will be conducted in patients, 65 years and above undergoing elective total hip replacement surgery at AZ Sint-Jan (Brugge, Belgium) to assess patients' basic knowledge regarding PND.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 65 Years 至 —(Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age 65 and above
- •ASA score 1 to 3
- •scheduled for elective hip surgery.
排除标准
- •insufficient knowledge of Dutch
- •known neuropsychiatric conditions
结局指标
主要结局
PND knowledge
时间窗: 1 week pre-operatively
Patient knowledge regarding PND will be evaluated through 15 yes/no questions
次要结局
- Baseline cognition(1 week pre-operatively)
- PND(6 weeks post-operatively)
研究者
Sarah Saxena
PI
Université Libre de Bruxelles
