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临床试验/NCT05590845
NCT05590845招募中不适用

Evaluating Patient Knowledge About Perioperative Neurocognitive Disorders (KNOW-PND Study)

Université Libre de Bruxelles1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2023年1月15日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
100
试验地点
1
主要终点
PND knowledge

研究概览

简要总结

Neurocognitive disorders remain one of the major perioperative complications. They are associated with delayed recovery, prolonged length of hospital stay and impacts on patients' quality of life. The incidence of PND ranges from 15-50%.

While several causes have been investigated, PND seems to be due to the non-resolution of an inflammatory cascade, making some patients more at risk than others. As such, major risk factors include old age and lower education levels.

As the global proportion of people aged 60 and above between 2015 and 2050 will increase from 12% to 22% and worldwide surgeries increases to >300 million procedures per annum the incidence of perioperative neurocognitive disorders with high morbidity and mortality will go up.

In 2015, the American Society of Anesthesiologists (ASA) launched the 'Perioperative Brain Health Initiative' to increase awareness about perioperative neurocognitive disorders. (PND) While physicians seems to be more and more aware about this condition, data regarding patient awareness are not available.

An observational, single-centre, cross-sectional survey study (with initially a feasibility study) will be conducted in patients, 65 years and above undergoing elective total hip replacement surgery at AZ Sint-Jan (Brugge, Belgium) to assess patients' basic knowledge regarding PND.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
65 Years 至 —(Older Adult)
性别
All
接受健康志愿者

入选标准

  • age 65 and above
  • ASA score 1 to 3
  • scheduled for elective hip surgery.

排除标准

  • insufficient knowledge of Dutch
  • known neuropsychiatric conditions

结局指标

主要结局

PND knowledge

时间窗: 1 week pre-operatively

Patient knowledge regarding PND will be evaluated through 15 yes/no questions

次要结局

  • Baseline cognition(1 week pre-operatively)
  • PND(6 weeks post-operatively)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Sarah Saxena

PI

Université Libre de Bruxelles

研究点 (1)

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