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临床试验/NCT04071834
NCT04071834已完成不适用

Effect of Subarachnoid Anesthesia on Blood Orphanin and Norepinephrine in Diabetic Patients

Second Hospital of Shanxi Medical University1 个研究点 分布在 1 个国家目标入组 120 人开始时间: 2019年10月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
120
试验地点
1
主要终点
Blood orphanin concentration

研究概览

简要总结

This study aims to investigate the Influence of Intraspinal anesthesia to the concentrations of blood orphanin, norepinephrine in patients with diabetes mellitus. We hope to explain the relationship between sensory and sympathetic nerves in diabetic patients undergoing intraspinal anesthesia.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
18 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients undergoing lower limb surgery under spinal anesthesia

排除标准

  • Emergency surgery
  • The operation time is more than 3 hours
  • Combined general anesthesia or nerve block anesthesia

结局指标

主要结局

Blood orphanin concentration

时间窗: 24 hours

Concentration of blood orphanin in patients before and after anesthesia

Blood norepinephrine concentration

时间窗: 24 hours

Concentration of blood norepinephrine in patients before and after anesthesia

次要结局

未报告次要终点

研究者

发起方
Second Hospital of Shanxi Medical University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Zheng Guo

professor

Second Hospital of Shanxi Medical University

研究点 (1)

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