临床试验/NCT01220791

NCT01220791Unknown4 期

Methylprednisolone vs. Placebo to Control Late Follicular Progesterone Elevation in GnRH-Antagonist IVF Cycles

Universitair Ziekenhuis Brussel2 个研究点分布在 1 个国家目标入组 130 人开始时间: 2009年1月最近更新: 2010年10月14日

适应症

试验速览

阶段: 4 期
发起方: Universitair Ziekenhuis Brussel
入组人数: 130
试验地点: 2
主要终点: Progesterone rise above 1.5ng.ml on the day of HCG

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

Hypothesis to be tested is whether follicular addition of Methylprednisolone can efficiently control late follicular progesterone rise during IVF treatment

详细描述

The aim is to investigate any potential advantages of adding cortisone supplementation from the follicular phase onwards with regard to premature luteinization, oocyte quality, embryo quality and pregnancy outcome.

研究设计

研究类型: Interventional
分配方式: Randomized
干预模型: Parallel
主要目的: Treatment
盲法: Single (Investigator)

入排标准

年龄范围: 21 Years 至 36 Years（Adult）
性别: Female
接受健康志愿者: 否

入选标准

•less than 36, more than 10 antral follicles, FSH<12

排除标准

•endometriosis stage III&IV,

结局指标

主要结局

Progesterone rise above 1.5ng.ml on the day of HCG

时间窗: up to 14 days of follicular ovarian stimulation

Incidence or high progesterone on the day of HCG triggering

次要结局

Clinical pregnancy rate(Follow pregnancy until delivery)

研究者

发起方

Universitair Ziekenhuis Brussel

申办方类型

Other

研究点 (2)

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