An exploratory study on the association between squamous cell carcinoma occurrence and upper gastrointestinal microbiota in patients with laryngopharyngeal cancer
Not Applicable
Recruiting
- Conditions
- aryngopharyngeal cancer
- Registration Number
- JPRN-UMIN000043963
- Lead Sponsor
- The Jikei University School of Medicine
- Brief Summary
Testing ongoing
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 10
Inclusion Criteria
Not provided
Exclusion Criteria
1.Patients whom the principal investigator determined to be inappropriate to participate in the study 2. Patients under the age of 20 3. Patients who are pregnant 4. Patients who underwent antibiotic treatment within a month 5. Patients who took proton pump inhibitors within a month
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Microbial profile between the patients with laryngopharyngeal cancer and healthy subjects 1) Relative abundance at the level of phylum/genus/OTU level 2) Alfa-diversity [Shannon index, Chao1 index, ACE, Number of observed OTUs] 3) Beta-diversity [weighted and unweighted UniFrac distance-based analysis]
- Secondary Outcome Measures
Name Time Method