EUCTR2007-007970-47-DE进行中（未招募）不适用
Central nervous effects of exendin-4 on hunger and satiety in obesity and diabetes mellitus type 2: an fMRI study - Neuroimaging and Obesity
niversity of Leipzig0 个研究点开始时间: 2009年8月5日最近更新:
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相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- Male
入选标准
- •All subjects:
- •- age 18-45 years
- •- BMI =30 kg/m²
- •- non vegetarians
- •- right handedness
- •- informed consent
- •- normal/ corrected to normal vision
- •- German native speaker
- •Subjects with typ2 diabetes mellitus:
- •- antidiabetic medicatio: metformin or sulfonylureas
- •- duration od diabetes = 2 years
- •- HbA1c > 6.5%
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range
排除标准
- •Subjects with T2D:
- •- anti.diabetes drugs other than sulfonylureas or metformin
- •All subjects:
- •- eating disorders
- •- chronic diseases, other than T2D, hyperlipidemia or hypertension
- •- chronic kidney failure = 2 KDOQI
- •- mental disease or retardation with impaired jugdement power
- •- epilepsia
- •- claustrophobia
- •- alcohol addiction
- •- endocrine diseases
- •- flu-like symptoms in the previous 2 weeks
- •- no informed consent
- •- metallic implants/devices, e. g. pace maker
- •- participation in another interventional trial or trial liable to insurance deductions
- •- contraindications for study medication (e.g. hypersensitivity to ingredients- e.g. metacresol/ contraindications according SmpC/ against albumin/ plasma proteins)
- •- non-compliance
- •- medical therapy (especially for weight control): except antihypertensive drugs/ lipid lowering drugs
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