Action of Caffeinated and Decaffeinated Espresso on Autonomic Function

Not Applicable

Terminated

• Conditions: Influence of Espresso on Heart Rate Variability
• Interventions: Other: hab cof with water; Other: non-hab cof with water; Other: hab cof with dec espresso; Other: non-hab cof with dec espresso; Other: hab cof with caf espresso; Other: non-hab cof with caf espresso

• Registration Number: NCT00576030
• Lead Sponsor: Charite University, Berlin, Germany

Brief Summary

More than 80% of the population in the USA consume coffee each day. However there not many studies on change of heart rate variability and placebo effects after consumption of coffee.

In our study we aim to test the following hypotheses:

1. Habitual caffeinated espresso coffee drinkers show an increase in blood pressure, heart rate variability and parasympathetic activity (high frequency band) of the heart.

2. Non-habitual caffeinated espresso coffee drinkers show an increase of blood pressure. The heart rate variability and the parasympathetic activity of the heart will decrease.

3. Caffeinated or decaffeinated espresso induces comparable changes in habitual or non-habitual coffee drinkers.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-01
• Study First Submitted: 2007-12-14
• Study First Submitted QC: 2007-12-17
• Study First Posted: 2007-12-18
• Primary Completion: 2008-10
• Study Completion: 2008-10
• Status Verified: 2009-08
• Last Update Submitted: 2010-07-02
• Last Update Posted: 2010-07-05

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 77

Inclusion Criteria

• 18- 50 years old, healthy

Exclusion Criteria

• Medication, obese(BMI > 30)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
H	hab cof with water	habitual coffee drinkers
H	hab cof with dec espresso	habitual coffee drinkers
H	hab cof with caf espresso	habitual coffee drinkers
N	non-hab cof with water	non-habitual coffee drinkers
N	non-hab cof with dec espresso	non-habitual coffee drinkers
N	non-hab cof with caf espresso	non-habitual coffee drinkers

Primary Outcome Measures

Name	Time	Method
Heart rate variability	70 minutes

Secondary Outcome Measures

Name	Time	Method
blood pressure	70 min.

Trial Locations

Locations (1)

Department of Psychosomatic Medicine and Psychotherapy, Charité University; 🇩🇪 Berlin, Germany