Left Ventricular Dysfunction in Critically Ill Patients
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Left Ventricular Dysfunction
- Sponsor
- Sahlgrenska University Hospital, Sweden
- Enrollment
- 428
- Locations
- 1
- Primary Endpoint
- Mortality
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
Left ventricular dysfunction is common in the critically ill. The aim of this study is to assess the incidence and prognosis of left ventricular dysfunction in critically ill patients.
Detailed Description
Left ventricular dysfunction is common in the critically ill. A number of conditions can cause left ventricular dysfunction including myocardial infarction, septic cardiomyopathy, post resuscitation syndrome, takotsubo syndrome etc. A number of studies have assessed cardiac dysfunction in specific conditions (e.g. sepsis, cardiac arrest) but only a few studies have assessed cardiac dysfunction in a general ICU-population. The study will focus on diagnostics of the different types of cardiomyopathy and differentiating between ischemic and non-ischemic left ventricular dysfunction in a general ICU population. The aim of this study is to assess the incidence and prognosis of the different types of left ventricular dysfunction in critically ill patients. Our hypothesis is that left ventricular dysfunction is common in the critically ill and is associated with an increased risk of short-term death.
Investigators
Jonatan Oras
Consultant, adjunct senior lecturer
Sahlgrenska University Hospital, Sweden
Eligibility Criteria
Inclusion Criteria
- •Admitted within 24 hours to the ICU
- •Dysfunction of at least one organ system, defined as at least +1 point in SOFA-score.
- •Exclusion Criteria
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Mortality
Time Frame: 30 days
All cause mortality after admission to the ICU