Right Ventricle Dysfunction in Critically Ill Patients

Not yet recruiting

• Conditions: Right Ventricular Dysfunction

• Registration Number: NCT05975086
• Lead Sponsor: Assiut University

Brief Summary

To assess prevalence of right ventricle dysfunction in critically ill patient. To assess impact of RV dysfunction on short term (ICU stay, hospital stay, or mortality ≤30 days) and long term outcome (\>30 days).

To assess the accuracy of different parameters of RV dysfunction.

Detailed Description

1. Inclusion criteria:

- Adult patients who admitted to critical care of Internal medicine department after obtaining consent during the period between august 2023 and august 2024.

2. Exclusion criteria:

1. Children below 18 yr.

2. Patients who could not be scanned within 48h after ICU admission.

3. Sample Size Calculation:

200 patients 2.4.4 Study tools (in detail, e.g., lab methods, instruments, steps, chemicals, ):

Beside history and clinical examination , The following data will be obtained:

Demographic and historical data: the patient age, sex, history of hypertension, chronic obstructive pulmonary disease, IHD, cause of critical care unit admission and indication of mechanical ventilation( PEEP).

Clinical examination data: pulse, blood pressure, respiratory rate, temperature , BMI, and thorough chest, cardiac examination data will be obtained.

Volume state of the patient: CVP measurement, input and output fluid chart. APACHE IV score, Use of vasopressors, Use of sedatives. Investigation : Arterial blood gas analysis, pulse oxygen saturation, CBC, and renal function test and electrolytes, serum lactate and troponin.

12 lead ECG for RV strain patterns.

Study Timeline

• Status Verified: 2023-07
• Study First Submitted: 2023-07-27
• Study First Submitted QC: 2023-07-27
• Last Update Submitted: 2023-07-27
• Study First Posted: 2023-08-03
• Last Update Posted: 2023-08-03
• Study Start: 2023-08-30
• Primary Completion: 2024-08-01
• Study Completion: 2024-09-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• Adult patients who admitted to critical care of Internal medicine department after obtaining consent during the period between august 2023 and august 2024.

Exclusion Criteria

1. Children below 18 yr.
2. Patients who could not be scanned within 48h after ICU admission.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Impact of right ventricle dysfunction in Critically ill patients on short term and long term outcome	Baseline	To assess prevalence of right ventricle dysfunction in critically ill patient. To assess impact of RV dysfunction on short term (ICU stay, hospital stay, or mortality ≤30 days) and long term outcome (\>30 days).

Secondary Outcome Measures

Name	Time	Method
Impact of right ventricle dysfunction in Critically ill patients on short term and long term outcome	Baseline	To assess prevalence of right ventricle dysfunction in critically ill patient. To assess impact of RV dysfunction on short term (ICU stay, hospital stay, or mortality ≤30 days) and long term outcome (\>30 days).