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Clinical Trials/NCT05193682
NCT05193682
Not Yet Recruiting
N/A

Evaluation Of Right Ventricular Function In Septic Shock Patients In Intensive Care Unit.

Shimaa Hammad Ahmed0 sites25 target enrollmentOctober 2022
ConditionsSeptic Shock

Overview

Phase
N/A
Intervention
Not specified
Conditions
Septic Shock
Sponsor
Shimaa Hammad Ahmed
Enrollment
25
Primary Endpoint
Right ventricular dysfunction in septic shock patients in intensive care unit
Status
Not Yet Recruiting
Last Updated
3 years ago

Overview

Brief Summary

Assesment of right ventricular dysfunction in septic shock patients in intensive care unit.

Detailed Description

Over the last decade, a few studies have highlighted the crucial role of right ventricular (RV) function in hemodynamic and respiratory diseases in critical care 1,2. However, RV failure is difficult to define in the critical care setting. A recent consensual definition proposed by different groups of experts characterizes RV failure as the association of a significant RV dilatation associated with systemic congestion 3-5. This definition is mainly physiologically based, not strictly validated, and the experts did not propose any threshold for RV size or congestion using critical care echocardiography (CCE) and central venous pressure (CVP), respectively. Fluid management in septic shock is crucial for prognosis, as fluid overload and high CVP are associated with a worse outcome 6. Septic shock is expected to impair RV function through the development of septic cardiomyopathy, but the incidence of RV failure is unknown.

Registry
clinicaltrials.gov
Start Date
October 2022
End Date
March 2023
Last Updated
3 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Shimaa Hammad Ahmed
Responsible Party
Sponsor Investigator
Principal Investigator

Shimaa Hammad Ahmed

Resident doctor at critical care unit

Assiut University

Eligibility Criteria

Inclusion Criteria

  • Patients diagnosed with septic shock.
  • Patients will be evaluated within 24 h after diagnosis.

Exclusion Criteria

  • Patients diagnosed more than 24 hours.
  • Patients with associated ischemic heart failure .

Outcomes

Primary Outcomes

Right ventricular dysfunction in septic shock patients in intensive care unit

Time Frame: 3 years

Fluid management in septic shock is crucial for prognosis, as fluid overload and high CVP are associated with a worse outcome 6. Septic shock is expected to impair RV function through the development of septic cardiomyopathy, but the incidence of RV failure is unknown.

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