Effects of flaxseed oil on hematologic factors, serum concentrations of hepcidin and cardiovascular risk factors in hemodialysis patients
Not Applicable
- Conditions
- Chronic Kidney Disease (Hemodialysis).
- Registration Number
- IRCT201412192716N3
- Lead Sponsor
- ational Nutrition and Food Technology Research Institute
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 16
Inclusion Criteria
Inclusion criterion: being on hemodialysis at least 6 months. Exclusion criteria: infections; inflammatory diseases; receiving anti-inflammatory drugs.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Systemic inflammation markers (hs-CRP, bone turnover markers). Timepoint: Baseline & week 8. Method of measurement: ELISA.
- Secondary Outcome Measures
Name Time Method Hematologic factors (Hb, HCT, RBC, MCV, MCH, MCHC). Timepoint: Baseline, week 8. Method of measurement: Cell counter.;Hepcidin. Timepoint: Baseline, week 8. Method of measurement: ELISA.;Vascular inflammation markers (ICAM-1, VCAM-1, E-selectin). Timepoint: Baseline, week 8. Method of measurement: ELISA.;Oxidative stress (MDA). Timepoint: Baseline, week 8. Method of measurement: Colorimetery.;Lipid profile (TG,TC,LDL-C,HDL-C, Lp(a)). Timepoint: Baseline, week 8. Method of measurement: Lp(a) by ELISA; TG,TC,HDL-C by colorimetry; LDL-C by Frieldwald formula.