Comparison of low dose spinal anaesthesia and nerve blocks for below knee amputation surgery in patients with diabetic foot infections
Not Applicable
- Conditions
- Health Condition 1: E116- Type 2 diabetes mellitus with other specified complications
- Registration Number
- CTRI/2020/01/022700
- Lead Sponsor
- Jawaharlal Institute of Postgraduate Medical Education and Research JIPMER
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients with diabetic foot infection posted for Emergency below knee amputation surgery
Exclusion Criteria
Patients who are in vasopressor/inotropic support.
Patients who are in coagulopathy (INR > 1.5 or platelet <80,000/μL)
Patients with Systolic BP less than 80 mm Hg.
Patients who are unable to cooperate for the procedure.
Local infection at procedural site.
Patients who are allergic to local anesthetics
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Comparison of percentage decrease in systolic blood pressure (SBP) from the baseline between the two groups (Group low dose subarachnoid block and Group femoral-popliteal block)Timepoint: Baseline, every two minutes for first 10 minutes after intervention and every 5 minutes till the end of surgery
- Secondary Outcome Measures
Name Time Method Comparison of mean intra-operative fluid used between the groupsTimepoint: From the intervention to the end of surgery, amount of intravenous fluid administered will be documented;Comparison of mean vasopressor use intra-operatively (to maintain a minimum MAP of 65 mm-Hg) between the groups. <br/ ><br>Timepoint: From the intervention to the end of surgery, requirement of vasopressor will be documented;Comparison of pH, pCO2, lactate and bicarbonate between the groupsTimepoint: Before the intervention and at the end of surgery