EFFECT OF DEXMEDETOMIDINE ON HEART RATE AND BLOOD PRESSURE RESPONSES TO DOUBLE LUMEN TUBE INSERTION UNDER GENERAL ANAESTHESIA
Not Applicable
Completed
- Conditions
- Health Condition 1: null- ASA physical status I-II, Age 18â??65 years undergoing scheduled thoracic surgery requiring double lumen tube for isolation of lungs
- Registration Number
- CTRI/2015/08/006066
- Lead Sponsor
- Tata Memorial Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 50
Inclusion Criteria
ASA physical status I-II,
Age 18â??65 years undergoing scheduled thoracic surgery requiring double lumen tube for isolation of lungs
Exclusion Criteria
H/O allergy to study drug,ASA III and IV,Mallampati Grade 3 and 4,Patient with Heart Block /Pacemaker /HR <50/min or 100/min,Patient on B- blockers,Preoperative arrhythmias,Coronary artery disease,Previous cerebrovascular disease,Renalimpairment (S Cr >1.5),Liver impairment,Poorly controlled hypertension,Patient refusal,Pregnancy,
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes in hemodynamic parameters- HR,SBP,DBP, MAP,RPP will be observedTimepoint: Changes in hemodynamic parameters- HR,SBP,DBP, MAP,RPP will be observed at the following time intervals <br/ ><br>Preanaesthetic Checkup. <br/ ><br>Baseline â?? on OT table. <br/ ><br>Beginning and end of infusion. <br/ ><br>Before intubation(3 mins after anaesthetic induction), during intubation at 0 mins and after one minute intervals till 10 mins of intubation. <br/ ><br>
- Secondary Outcome Measures
Name Time Method Adverse effects- hypotension, hypertension, bradycardia, airway obstruction will be observedTimepoint: Adverse effects like hypotension, hypertension, bradycardia, airway obstruction will be observed during the procedure