The Impact of Adequate Water Intake on Exercise Performance and Mood in Women and Men

Not Applicable

Completed

• Conditions: Mood; Dehydration
• Interventions: Behavioral: Increase water consumption; Behavioral: Maintain adequate water consumption

• Registration Number: NCT05033665
• Lead Sponsor: Arizona State University

Brief Summary

Dehydration is defined as the state of water deficit due to excessive water losses and/or small water intake. Underhydration is the result of inadequate water intake leading to activation of water hormonal homeostasis, characterized by elevated vasopressin, lower urinary output, and concentrated urine without any measurable changes in total body water. It is well established that dehydration (water deficit) decreases exercise performance and worsens mood, mainly in women. However, the impact of increased water intake in underhydrated individuals on their exercise capacity and mood is not known.

The aim of the proposed study is to investigate the impact of increased water intake in underhydrated individuals on aerobic exercise performance and mood in both women and men.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-05-26
• Study First Submitted: 2021-08-25
• Study First Submitted QC: 2021-09-01
• Study First Posted: 2021-09-05
• Primary Completion: 2023-04-26
• Study Completion: 2023-04-26
• Status Verified: 2023-08
• Last Update Submitted: 2023-08-23
• Last Update Posted: 2023-08-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 217

Inclusion Criteria

• Healthy adults
• Residence in Arizona

Exclusion Criteria

• Use of diuretics
• Use of anti-depressive medication
• Current pregnancy or lactation
• Current use of injectable insulin
• Diagnosed with irritable bowel syndrome
• Do not pass the Physical Activity Readiness Questionnaire for Everyone (PAR-Q) screening

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Underhydrated	Increase water consumption	Afternoon urine osmolality ≥ 800 mmol/kg or urine specific gravity ≥ 1.020.
Euhydrated	Maintain adequate water consumption	Afternoon urine osmolality \< 800 mmol/kg or urine specific gravity \< 1.020.

Primary Outcome Measures

Name	Time	Method
2-mile run-time (min)	Day 8
Urine specific gravity	Upon waking (first morning sample) on day 8
Mood	Post-trial on day 8	Profile of Mood States questionnaire (POMS 2®-Adult Short, Multi-Health Systems Inc.)
Urine osmolality (mmol/kg)	Upon waking (first morning sample) on day 8

Secondary Outcome Measures

Name	Time	Method
Urine color	Upon waking (first morning sample) on day 8	Armstrong validated 8-color scale. Minimum score: 1. Maximum score: 8. A higher score indicates a worse outcome (e.g., dehydrated).
Thirst perception	Upon waking (first morning sample) on day 8	175 mm visual analog scale. Minimum score: 0 (not thirsty at all). Maximum score: 175 (extremely thirsty). A higher score indicates a worse outcome (e.g., more thirsty).

Trial Locations

Locations (1)

Interdisciplinary Science and Technology Building 8; 🇺🇸 Phoenix, Arizona, United States