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The lying in prone position effect on oxygen saturation in patients in early stage and not intubated having mild to moderate Lung Disease with COVID-19

Not Applicable
Conditions
Health Condition 1: J80- Acute respiratory distress syndromeHealth Condition 2: B972- Coronavirus as the cause of diseases classified elsewhere
Registration Number
CTRI/2020/11/029130
Lead Sponsor
AIIMS Patna
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1.COVID-19 induced mild to moderate ARDS

2.Onset within one week of COVID-19

3.SpO2/FiO2 140-315

4.PF Ratio 100-300 mmHg

5.Bilateral changes on chest imaging

6.Not fully explained by cardiac failure

7.Patients between the ages of 18-75 years

8.Male and female

9. BMI 18-30kg/m2

10. Oxyhemoglobin saturation (SpO2) <=94% while receiving supplemental oxygen 6 L/min via nasal cannula and 15 L/min via non-rebreather facemask or with FiO2 0.3-0.6 (If HFNC or NIV)

Exclusion Criteria

1Need for immediate intubation

2RR >40

3PaO2/FiO2 <100

4SpO2/FiO2 <140

5Obvious accessory muscle use

6HR >100

7Systolic BP <100 mm Hg

8Unable/unwilling to participate to trial

9Unreliable SpO2 Trace

10Pregnancy >20/40 gestation

11Altered mental status with inability to turn in bed without assistance

12Multi-organ failure

13Contraindication to PP (e.g. vomiting, abdominal wound, unstable pelvic/spinal lesions, severe brain injury).

14Unable to maintain prone position

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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