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Clinical Trials/NCT00786292
NCT00786292
Completed
Not Applicable

Evaluation of Variable Pressure Support Ventilation in the Therapy of Acute Lung Injury (EVA-Trial)

Technische Universität Dresden1 site in 1 countryJuly 2009
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ConditionsAcute Lung Injury

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Acute Lung Injury
Sponsor
Technische Universität Dresden
Locations
1
Primary Endpoint
Effect on the arterial oxygenation
Status
Completed
Last Updated
13 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

Variable pressure support during assisted spontaneous breathing (noisy PSV) has been shown to improve the respiratory function in experimental acute lung injury (ALI). We aimed at comparing the effects of noisy PSV with traditional PSV on the respiratory function of patients suffering from ALI.

Registry
clinicaltrials.gov
Start Date
July 2009
End Date
September 2012
Last Updated
13 years ago
Study Type
Interventional
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

PD Dr. Marcelo Gama de Abreu

Prof. Dr.

Technische Universität Dresden

Eligibility Criteria

Inclusion Criteria

  • •age 18 to 75 yrs
  • •150 mmHg \< PaO2/FIO2 \< 300 mmHg
  • •mechanical ventilation with PSV or BIPAP
  • •less than 15 days of mechanical ventilation
  • •at least 20% of minute ventilation originated from spontaneous breathing

Exclusion Criteria

  • •BMI \> 35
  • •esophageal disease
  • •neuromuscular disease
  • •instable thorax
  • •pneumothorax
  • •head trauma
  • •brain injury
  • •increased intracranial pressure
  • •agitation
  • •increased need for vasoactive drugs

Outcomes

Primary Outcomes

Effect on the arterial oxygenation

Secondary Outcomes

  • Effect on the work of breathing
  • Effect on PaCO2

Study Sites (1)

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