Intermittent Fasting and Insulin SensitivityIn Lean Healthy Male Subjects.
- Conditions
- insulin resistance, intermittent fasting
- Registration Number
- NL-OMON28815
- Lead Sponsor
- M.J.Serlie M.D. PhDDept. of Endocrinology and MetabolismF5-167Academic Medical CentreMeibergdreef 91105 AZ AMSTERDAM+31205669111M.R.Soeters@amc.uva.nl
- Brief Summary
1: Pro OGTT Soeters MR, Serlie MJ. Ned Tijdschr Geneeskd. 2009 Apr 18;153(16):742. Dutch. <br> 2:Effects of Insulin on Ketogenesis Following Fasting in Lean and Obese Men. Soeters MR, Sauerwein HP, Faas L, Smeenge M, Duran M, Wanders RJ, Ruiter AF, Ackermans MT, Fliers E, Houten SM, Serlie MJ. Obesity (Silver Spring). 2009 Feb 19. [Epub ahead of print] <br> 3: Type 2 iodothyronine deiodinase in skeletal muscle: effects of hypothyroidism and fasting. Heemstra KA, Soeters MR, Fliers E, Serlie MJ, Burggraaf J, van Doorn MB, van der Klaauw AA, Romijn JA, Smit JW, Corssmit EP, Visser TJ. J Clin Endocrinol Metab. 2009 Jun;94(6):2144-50. Epub 2009 Mar 17. <br> 4: Muscle acylcarnitines during short-term fasting in lean healthy men. Soeters MR, Sauerwein HP, Duran M, Wanders RJ, Ackermans MT, Fliers E, Houten SM, Serlie MJ. Clin Sci (Lond). 2009 Apr;116(7):585-92. <br> 5: Muscle adaptation to short-term fasting in healthy lean humans. Soeters MR, Sauerwein HP, Dubbelhuis PF, Groener JE, Ackermans MT, Fliers E, Aerts JM, Serlie MJ. J Clin Endocrinol Metab. 2008 Jul;93(7):2900-3. Epub 2008 Apr 8. <br> 6: Gender-related differences in the metabolic response to fasting. Soeters MR, Sauerwein HP, Groener JE, Aerts JM, Ackermans MT, Glatz JF, Fliers E, Serlie MJ. J Clin Endocrinol Metab. 2007 Sep;92(9):3646-52. Epub 2007 Jun 12. <br> 7: Recombinant human C1-inhibitor in the treatment of acute angioedema attacks. Choi G, Soeters MR, Farkas H, Varga L, Obtulowicz K, Bilo B, Porebski G, Hack CE, Verdonk R, Nuijens J, Levi M. Transfusion. 2007 Jun;47(6):1028-32.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 8
1. Lean healthy male volunteers;
2. Age 18 - 35 years;
1. Any medication;
2. DM II in first degree family members;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method