A Real-world Study for Patients With Multiple Pulmonary Ground-glass Nodules

Not yet recruiting

• Conditions: Multiple Pulmonary Nodules

• Registration Number: NCT04192201
• Lead Sponsor: Tongji Hospital

Brief Summary

The purpose of this study is to actively monitor patients with multiple pulmonary Ground-glass Nodules (GGNs), in order to provide evidence for multiple GGNs treatment.

Detailed Description

Multiple pulmonary GGNs are very commonly identified particularly as increasing numbers of CT scans are performed as part of routine lung cancer screening. At the same time, the ideal solution for these cases continues to be debated. This aim of this study is to learn more about the effects of multiple factors on outcome of multiple pulmonary GGNs, such as patients' clinical characteristics, CT features and different pathological types. Furthermore, the optimal timing of surgery and the effect of different surgical choices on the prognosis of patients with multiple GGNs will be investigated.

Study Timeline

• Study First Submitted: 2019-09-23
• Status Verified: 2019-10
• Study First Submitted QC: 2019-12-05
• Last Update Submitted: 2019-12-05
• Study First Posted: 2019-12-10
• Last Update Posted: 2019-12-10
• Study Start: 2019-12-31
• Primary Completion: 2021-12-31
• Study Completion: 2024-12-31

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

1. Age greater than 18 years
2. Have two or more GGNs on CT imaging
3. Diameter of GGNs > 5mm and ≤ 3cm
4. GGNs must be greater than half ground glass

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Exclusion Criteria

1. patients who have a history of lung cancer
2. patients who have undergone chemotherapy, radiotherapy or targeted therapy before surgery
3. pregnant women

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
5-year overall survival [Time Frame: From date of the recruitment, assessed up to 60 months]	October 31, 2024	5-year overall survival

Secondary Outcome Measures

Name	Time	Method
Recurrence-free survival [Time Frame: From date of the recruitment, assessed up to 60 months]	October 31, 2024	Recurrence-free survival
5-year Progression-Free-Survival [Time Frame: From date of the recruitment, assessed up to 60 months]	October 31, 2024	5-year Progression-Free-Survival

Trial Locations

Locations (1)

Tongji Hospital; 🇨🇳 Wuhan, Hubei, China