Cognitive Behavioral Therapy on Adherence and Depression (CBT-AD) Among HIV/AIDS Patients

Not Applicable

Recruiting

• Conditions: Depression; Medication Adherence

• Registration Number: NCT06109610
• Lead Sponsor: Mattu University

Brief Summary

Depression is highly comorbid with HIV/ AIDS and is associated with worse poor adherence to antiretroviral therapy (ART), and potentially to long-term immune functioning. Cognitive behavioral therapy may solve these problem.

Detailed Description

Depression is highly comorbid with HIV/ AIDS and is associated with worse poor adherence to antiretroviral therapy (ART), and potentially to long-term immune functioning. Poor adherence decreases the benefits of ART as well as chances of prolonged survival. An intervention that integrates CBT for depression with a cognitive behavioral approach to adherence counseling (cognitive behavioral therapy intervention for adherence and depression (CBT-AD)) has been found to be effective in improving adherence and reducing depression in PLWH.

Study Timeline

• Study Start: 2021-05-01
• Status Verified: 2023-10
• Study First Submitted: 2023-10-17
• Study First Submitted QC: 2023-10-28
• Last Update Submitted: 2023-10-28
• Study First Posted: 2023-10-31
• Last Update Posted: 2023-10-31
• Primary Completion: 2023-11-01
• Study Completion: 2023-11-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 128

Inclusion Criteria

• PLWHA who were 18 years old and above were included in the study

Exclusion Criteria

• PLWHA who were previously took CBT and participants with acute physical or mental disturbances were excluded.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
The mean score of Depression will change after intervention	Through study completion, an average of 1 yea	Depression is measured by Patient Health Questionnaire (PHQ-9) Depression Scale. The minimum value is 0 and the maximum value is 27. The higher score mean worse outcome

Trial Locations

Locations (1)

Mattu University; 🇪🇹 Addis Ababa, Ethiopia