Comparison of Two Different Approach TAP Block on Pain Management of Laparoscopic Nephrectomy

Not Applicable

Completed

• Conditions: Analgesia, Patient-Controlled; Postoperative Pain, Acute
• Interventions: Procedure: posterior tap block; Procedure: lateral tap block

• Registration Number: NCT05188794
• Lead Sponsor: Ankara City Hospital Bilkent

Brief Summary

Primary aim is to compare the effectiveness of the posterior approach Transversus abdominis plane block (P-TAP) and the lateral approach Transversus abdominis plane block (L-TAP) technique on the pain management of the laparoscopic nephrectomy in terms of visual analog pain scale and postoperative opioid consumption. Secondary aim is to compare complication rates of the two techniques.

Detailed Description

Patients included in the study will be randomized into two groups (group L and group P) in the preoperative period. Following routine anesthesia induction TAP block will be applied to group L patients with the lateral approach technique, and to group P patients with the posterior approach technique. Regional block complications will be recorded.

Standard laparoscopic nephrectomy surgical method will be applied. 1g of paracetamol and 4mg of dansetron will be administered to both groups 15 minutes before the end of the operation. The pain intensity of the patients will be questioned and VAS values will be recorded at 0, 1, 2, 6, 12 and 24 hours postoperatively.

Study Timeline

• Study First Submitted: 2021-11-22
• Study First Submitted QC: 2021-12-27
• Study Start: 2022-01-01
• Study First Posted: 2022-01-12
• Primary Completion: 2022-05-01
• Study Completion: 2022-05-15
• Status Verified: 2024-04
• Last Update Submitted: 2024-04-04
• Last Update Posted: 2024-04-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 88

Inclusion Criteria

• ASAI-III patients undergoing laparoscopic nephrectomy
• 18<BMI<40

Exclusion Criteria

• infection at the block site
• coagulation disorder
• pregnancy
• kidney failure
• liver failure
• heart failure
• allergy to local anesthetics
• patient refusal

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group P	posterior tap block	Posterior transversus abdominis plane block
group L	lateral tap block	Lateral transversus abdominis plane(TAP) block

Primary Outcome Measures

Name	Time	Method
Visual Analog Pain scale 12	Postoperative 12. hour	Patients will be asked about the severity of pain. They will be told that 0 = no pain, 10 = severe pain, and they will be asked to determine a number between 0 and 10 for the severity of pain.
Visual Analog Pain scale 2	Postoperative second hour	Patients will be asked about the severity of pain. They will be told that 0 = no pain, 10 = severe pain, and they will be asked to determine a number between 0 and 10 for the severity of pain.
Visual analog pain scale 6	Postoperative sixth hour	Patients will be asked about the severity of pain. They will be told that 0 = no pain, 10 = severe pain, and they will be asked to determine a number between 0 and 10 for the severity of pain.
Visual Analog Pain scale 18	Postoperative18. hour	Patients will be asked about the severity of pain. They will be told that 0 = no pain, 10 = severe pain, and they will be asked to determine a number between 0 and 10 for the severity of pain.
Visual Analog Pain scale 24	Postoperative 24. hour	Patients will be asked about the severity of pain. They will be told that 0 = no pain, 10 = severe pain, and they will be asked to determine a number between 0 and 10 for the severity of pain.
opioid comsuption	Within 24 hours postoperatively	Patients will be asked about the severity of pain. They will be told that 0 = no pain, 10 = severe pain, and they will be asked to determine a number between 0 and 10 for the severity of pain.
Visual analog pain scale 0	at the PACU arrival	Patients will be asked about the severity of pain. They will be told that 0 = no pain, 10 = severe pain, and they will be asked to determine a number between 0 and 10 for the severity of pain.
Visual analog pain scale 1	Postoperative first hour	Patients will be asked about the severity of pain. They will be told that 0 = no pain, 10 = severe pain, and they will be asked to determine a number between 0 and 10 for the severity of pain.

Trial Locations

Locations (1)

Ankara City Hospital,Bilkent; 🇹🇷 Ankara, Cankay, Turkey