跳至主要内容
临床试验/NCT02629900
NCT02629900Unknown不适用

The Effect of Time Restricted Feeding on Fat Mass in Overweight Women

University of Western Ontario, Canada2 个研究点 分布在 1 个国家目标入组 16 人开始时间: 2016年1月1日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
16
试验地点
2
主要终点
Fat mass change over 4 weeks period of intervention

研究概览

简要总结

Participants will complete a one-month intervention where they are will restrict their daily food intake to an 8-hour time period, i.e., between 1200 to 2000 hours. During the remaining 16-hour intermittent fasting period (2000 to 1200 hours) participants will be allowed to drink zero calorie beverages (diet soda pop, black coffee, tea, water, etc) in order to maintain normal hydration. There will be no attempt to restrict food intake. Rather simply to restrict the time period each day when food is consumed. Participants' body mass, fat mass, and non-fat mass will be monitored non-invasively using a weigh scale and densitometry via air displacement (Bod Pod) at 0, 2 and 4 weeks following the dietary intervention. Also, participants will be interviewed following the final body composition measure to assess whether or not they continued to follow the intermittent fasting approach.

详细描述

Participants (16 overweight women, BMI (Body mass index) ˃25, ages 18- 30 y)will complete a one-month intervention where they will restrict their daily food intake to an 8-hour time period, i.e., between 1200 to 2000 hours. During the remaining 16-hour intermittent fasting period (2000 to 1200 hours) participants will be allowed to drink zero calorie beverages (diet soda pop, black coffee, tea, water, etc) in order to maintain normal hydration. There will be no attempt to restrict food intake. Rather simply to restrict the time period each day when food is consumed. Participants' fat mass will be monitored non-invasively using densitometry (with a Bod Pod) prior to and following a 4 week intervention where the participants will eat their normal daily intake during an 8-hour period each day (1200 to 2000 hours). The Bod Pod measures body volume via air displacement and together with an accurate measure of body mass enables body density to be calculated (Density = mass/volume). Satisfaction, hunger, and fullness with the diet will be monitored on a weekly basis using a validated visual analog scale (Flit et al, 2000). Adherence to the diet will also be assessed on a weekly basis as the number of days the diet was followed. During the 16-hour fasting period participants will be able to drink as much of zero calorie beverages as they desire. On day 2, 7, 14, 21, & 28 participants will return to the lab at 8am (following a 12 hour fasting period) and both the acidity of their urine (using a urine dip stick) and their blood sugar (using a glucometer) will be tested. Following one month the participants will be allowed either to continue this eating pattern or revert to their prior 3 meal intake. After a month of self-regulation, the participants' fat mass will be measured again using the Bod Pod.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
盲法
None

入排标准

年龄范围
18 Years 至 30 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • Asymptomatic participants between the ages of 18-30 years with body mass index ˃25 will be studied

排除标准

  • Individuals with a history of fainting
  • Low blood sugar
  • Heart disease, migranes, or heart burn
  • Participants less then 18 of age
  • Anyone who for health or performance reasons should not skip breakfast will be excluded. These will be assessed by self report

结局指标

主要结局

Fat mass change over 4 weeks period of intervention

时间窗: 4 weeks

Body fat mass change (%) will be measured using BodPod over the course of 4 weeks at 0, 2 and 4 weeks

次要结局

  • Non-fat mass change over 4 weeks period of intervention(4 weeks)
  • Urine acidity change over 4 weeks of intervention(4 weeks)
  • Feeling of fullness change over 4 weeks of intervention(4 weeks)
  • Diet satisfaction change over 4 weeks of intervention(4 weeks)
  • Blood sugar change over 4 weeks of intervention(4 weeks)
  • Feeling of hunger change over 4 weeks of intervention(4 weeks)

研究者

发起方
University of Western Ontario, Canada
申办方类型
Other
责任方
Principal Investigator
主要研究者

Peter Lemon

PhD

University of Western Ontario, Canada

研究点 (2)

Loading locations...

相似试验

The Effect of Time Restricted Feeding on Fat Mass in... | 临床试验