Does pre-operative Sildenafil protect against pulmonary related complications following cardiopulmonary bypass? A randomised trial in children undergoing cardiac surgical repair

HS Greater Glasgow, Yorkhill0 个研究点目标入组 24 人开始时间: 2006年1月27日最近更新: 2019年11月25日

适应症

试验速览

暂无简介。

•Inclusion criteria
•- pediatric patients undergoing open heart surgery utilising cardiopulmonary bypass to correct acyanotic congenital heart disease
•- age >3 months
•- parents that show a good understanding of their child's condition and are happy for their child to participate in the study
•Are the trial subjects under 18? yes
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) no
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) no
•F.1.3.1 Number of subjects for this age range

•Exclusion criteria
•- patients with known organ dysfunction prior to surgery (pulmonary, renal or hepatic)
•- communication barriers resulting in poor basic comprehension of the proposed study (e.g. language barrier)
•- patients with cyanotic heart disease
•-patients undergoing heart surgery without the use of cardiopulmonary bypass
•- patients who do not tolerate oral Sildenafil (e.g. Vomiting) or whose surgery is subsequently cancelled

发起方

HS Greater Glasgow, Yorkhill