Values for lipid profile and markers for insulin sensitivity in 3- to 5-year-old healthy, normal-weight children in the Northern Netherlands.

Completed

• Conditions: metabool syndroom; dyslipidemia; metabolic syndrome; 10018424

• Registration Number: NL-OMON36895
• Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 70

Inclusion Criteria

1. Children, aged 3 to 5 years.
2. Normal weight, i.e. body mass index below the international cut-off points for overweight.
Age 3 years: BMI < 17.9 kg/m2 (boys) and BMI < 17.6 kg/m2 (girls).
Age 4 years: BMI < 17.6 kg/m2 (boys) and BMI < 17.3 kg/m2 (girls).
Age 5 years: BMI < 17.4 kg/m2 (boys) and BMI < 17.2 kg/m2 (girls).
3. No chronic disease.
4. Planned for adeno- and/or tonsillectomy.

Exclusion Criteria

1. Children under the age of 3 years and children 6 years of age or older.
2. Overweight, i.e. body mass index above the international cut-off points for normal weight.
Age 3 years: BMI * 17.9 kg/m2 (boys) and BMI * 17.6 kg/m2 (girls).
Age 4 years: BMI * 17.6 kg/m2 (boys) and BMI * 17.3 kg/m2 (girls).
Age 5 years: BMI * 17.4 kg/m2 (boys) and BMI * 17.2 kg/m2 (girls).
3. Chronic disease, other than ENT-infections.
4. Familiar hypercholesterolemia diagnosed in one or both parents.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Values for: total cholesterol, HDL-cholesterol, LDL-cholesterol, triglycerides,<br /><br>insulin, glucose and HbA1c.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable.</p><br>