Topiramate in the treatment of methamphetamine dependence
Phase 2
- Conditions
- methamphetamine dependence.mental and behavioral disorders due to use of other stimulants, dependence syndrome
- Registration Number
- IRCT201302251556N52
- Lead Sponsor
- Vice chancellor for research, Kurdistan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
Inclusion Criteria:Diagnosis of Methamphetamine dependence based on DSM-IV-TR ; Positive methamphetamine urinary test at the beginning of the study; age between 18-65
Exclusion Criteria
any other mental disorder on axis I except for depression;Any serious medical or neurological problem ,2- IQ <70; abusing other substances except for nicotine and methadone; history of Attention Defecit-Hyperactivity Disorder during childhood ; pregnancy and breast feeding; development of psychotic symptoms requiried pharmacotherapy; serious suicidal ideations
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Craving. Timepoint: Baseline and then weekly. Method of measurement: visual analogue craving scale.;Addiction severity. Timepoint: Baseline and at the end of the study. Method of measurement: by Addiction SeverityIndex.;Rate of use. Timepoint: Baseline and then weekly. Method of measurement: Urinary methamphetamine test.
- Secondary Outcome Measures
Name Time Method