The effect of adding topiramate (compared to placebo) in reducing withdrawal symptoms in opium-like substances in the substance-dependent patients
Not Applicable
- Conditions
- opioid withdrawal symptoms.Mental and behavioural disorders due to use of opioids
- Registration Number
- IRCT201307205280N14
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Male
- Target Recruitment
- 42
Inclusion Criteria
Individuals are included if they fulfil DSM-IV-TR criteria for opioid- like substance dependency. However, Patients are not included if they have opioid- like withdrawal syndrome during the recruitment period.
Exclusion criteria: concomitant use of alcohol, stimulants as well as benzodiazepines; having severe medical comorbidities; patients who start to take any psychiatric medication or any significant change in dose of medication during the study and follow-up period.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of subjective withdrawal symptoms. Timepoint: At the days: 1, 3, 5, 7 and 14. Method of measurement: (OWSC) opiate withdrawal symptoms checklist.
- Secondary Outcome Measures
Name Time Method