Milk Plus Exercise: A Novel Strategy to Treat Diabetes.
- Conditions
- Type 2 Diabetes
- Registration Number
- NCT02251301
- Lead Sponsor
- University of British Columbia
- Brief Summary
The purpose of this study is to investigate whether combining interval training with skim milk supplementation will result in improved glucose control and markers of cardiovascular health in people with type 2 diabetes. Participants will complete supervised interval training three times a week over a 12 week training period while consuming skim-milk, whey/casein protein drink, or a placebo beverage that does not contain any calories or vitamins/minerals immediately and 1 hour after each training session. After twelve weeks participants will repeat baseline tests to examine any effects of the intervention on their glucose control, fitness, blood vessel function, body composition, and blood markers of inflammation.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 52
- Aged between 40 and 75.
- Diagnosed with type 2 diabetes for more than 6 months.
- On stable medication for the last 6 months
- Type 2 diabetes controlled with exogenous insulin
- Uncontrolled hypertension (blood pressure >160/90 mmHg)
- History of heart disease, myocardial infarction or stroke
- Any other contraindications to exercise
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Change from baseline in glycemic control assessed by continuous glucose monitoring at end of week 12 of intervention Baseline, Week 12.
- Secondary Outcome Measures
Name Time Method Change from baseline in hemoglobin A1C percentage at end of week 12 of intervention. Baseline, Week 12. Change from baseline in fasting plasma glucose concentration at end of week 12 of intervention. Baseline, Week 12. Change from baseline in fasting plasma insulin concentration at end of week 12 of intervention. Baseline, Week 12. Change from baseline in flow mediated dilation of brachial artery at end of week 12 of intervention. Baseline, Week 12. Change from baseline in peak oxygen uptake as a measure of aerobic fitness at end of week 12 of intervention. Baseline, Week 12
Trial Locations
- Locations (1)
University of British Columbia, Okanagan.
🇨🇦Kelowna, British Columbia, Canada
University of British Columbia, Okanagan.🇨🇦Kelowna, British Columbia, Canada