The Effect of Adding Milk in Proximity to Exercise During an Interval Training Intervention in Type 2 Diabetes (T2D) on Metabolic and Cardiovascular Health.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 52
- 试验地点
- 2
- 主要终点
- Change from baseline in glycemic control assessed by continuous glucose monitoring at end of week 12 of intervention
研究概览
简要总结
The purpose of this study is to investigate whether combining interval training with skim milk supplementation will result in improved glucose control and markers of cardiovascular health in people with type 2 diabetes. Participants will complete supervised interval training three times a week over a 12 week training period while consuming skim-milk, whey/casein protein drink, or a placebo beverage that does not contain any calories or vitamins/minerals immediately and 1 hour after each training session. After twelve weeks participants will repeat baseline tests to examine any effects of the intervention on their glucose control, fitness, blood vessel function, body composition, and blood markers of inflammation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 40 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Aged between 40 and
- •Diagnosed with type 2 diabetes for more than 6 months.
- •On stable medication for the last 6 months
排除标准
- •Type 2 diabetes controlled with exogenous insulin
- •Uncontrolled hypertension (blood pressure >160/90 mmHg)
- •History of heart disease, myocardial infarction or stroke
- •Any other contraindications to exercise
结局指标
主要结局
Change from baseline in glycemic control assessed by continuous glucose monitoring at end of week 12 of intervention
时间窗: Baseline, Week 12.
次要结局
- Change from baseline in fasting plasma insulin concentration at end of week 12 of intervention.(Baseline, Week 12.)
- Change from baseline in flow mediated dilation of brachial artery at end of week 12 of intervention.(Baseline, Week 12.)
- Change from baseline in hemoglobin A1C percentage at end of week 12 of intervention.(Baseline, Week 12.)
- Change from baseline in fasting plasma glucose concentration at end of week 12 of intervention.(Baseline, Week 12.)
- Change from baseline in peak oxygen uptake as a measure of aerobic fitness at end of week 12 of intervention.(Baseline, Week 12)