Reliability Study of a 3D Free-hand Ultrasonography Technique (3DfUS) in Combination With Instrumented Spasticity Assessment (ISA) for the Lower Limb in Chronic First-ever Stroke Patients.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 76
- 试验地点
- 1
- 主要终点
- Muscle and Tendon Length
研究概览
简要总结
The aim of this study is to investigate lower limb muscles after cerebrovascular accident
详细描述
The aim of this study is to define and differentiate the changes in MMT properties related to the alterations in muscle tone of the lower limb in first-ever chronic stroke patients by using a 3D free-hand Ultrasonography (3DfUS) technique in combination with an instrumented spasticity assessment (IPSA). In these chronic stroke patients, the spontaneous neurological recovery is stabilized
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Definition of case population :
- •o first ever stroke with spasticity of the lower limb.
- •Definition of control :
- •first ever stroke without spasticity of the lower limb
- •healthy aged-matched subjects
排除标准
- •Musculoskeletal or neurological problems affecting the lower limb
- •Presence of other neurological pathology that could lead to spasticity, ataxia, dystonia
- •Cognitive problems that impede measurements
- •Severe co-morbidities
- •Peripheral spastic medication
结局指标
主要结局
Muscle and Tendon Length
时间窗: 1 day
Estimation of muscle volume by 3D freehand ultrasonography
Echogenicity intensity
时间窗: 1 day
Estimation of echogenicity intensity by 3D freehand ultrasonography on an 8-bit greyscale (256 values).
Work [J] derived from the slow stretch
时间窗: 1 day
Measurement of Work \[J\] by Instrumented Spasticity Assessment
Muscle activity EMG [uV] derived from the fast stretch
时间窗: 1 day
Measurement of Muscle activity EMG \[uV\] by Instrumented Spasticity Assessment
Stiffness [Nm/deg] for slow stretch
时间窗: 1 day
Measurement of Stiffness \[Nm/deg\] by Instrumented Spasticity Assessment
Joint angle of catch [deg] from the fast stretch
时间窗: 1 day
Measurement of Joint angle of catch \[deg\] from the fast stretch by Instrumented Spasticity Assessment
Muscle volume
时间窗: 1 day
Estimation of muscle volume by 3D freehand ultrasonography.
Maximal velocity of performance (Vmax [deg/s])
时间窗: 1 day
Measurement of Maximal velocity of performance (Vmax \[deg/s\]) by Instrumented Spasticity Assessment
Angle of EMG threshold [deg] from the fast stretch
时间窗: 1 day
Measurement of Angle of EMG threshold \[deg\] by Instrumented Spasticity Assessment
Intensity of catch derived from the fast stretch
时间窗: 1 day
Measurement of Intensity of catch by Instrumented Spasticity Assessment
Range of motion [deg] for slow stretch
时间窗: 1 day
Measurement of Range of motion \[deg\] by Instrumented Spasticity Assessment
次要结局
- Clinical assessment of spasticity angle at slow and fast stretch(1 day)
- Clinical assessment of spasticity at fast stretch(1 day)