Effect of Nano curcumin on the severity of diabetic sensorimotor polyneuropathy
- Conditions
- E11.43Diadetic polyneuropathy.Type 2 diabetes mellitus with diabetic autonomic (poly)neuropathy
- Registration Number
- IRCT20140413017254N5
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 80
Age between 30 to 60 years old
desiration to participate in the study
Body mass index between25 - 39.9
Non-insulin diabetic patients type 2
Detection of mild sensorimotor polyneuropathy by using the Toronto questionnaire (score 6-8)
Follow a special diet during last month
Sensitivity to curcumin
Pregnancy and lactation
Eat any nutritional supplement, vitamin and mineral supplement last month
History of gastrointestinal ulcer and bile duct
There are neuropathies other than the sensory-motor polyneuropathy diabetic diagnosed by a neurologist
Take gabapentin and any medication
Diseases diagnosed, such as cancer, liver, kidney, autoimmune diseases, inflammatory, thyroid and nervous and cardiovascular diseases, and drug use associated with these diseases
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The severity of neuropathy in the Toronto questionnaire. Timepoint: Before the intervention, After intevention. Method of measurement: Toronto questionnaire.
- Secondary Outcome Measures
Name Time Method Fasting Blood Sugar. Timepoint: Before the intervention, After the intervention. Method of measurement: KIT.;Blood sugar 2 hour after meal. Timepoint: Before the intervention, After the intervention. Method of measurement: KIT.;HBA1C. Timepoint: Before the intervention, After the intervention. Method of measurement: KIT.