Propolis In The Treatment Of Periodontitis

Not Applicable

• Conditions: Chronic Periodontitis
• Interventions: Procedure: scaling root planing; Drug: Propolis

• Registration Number: NCT01943877
• Lead Sponsor: Rajarajeswari Dental College & Hospital

Brief Summary

This study was conducted to evaluate by clinical and microbiological parameters the effect of locally delivered propolis as an adjunct to scaling and root planing in the treatment of chronic periodontitis.

Detailed Description

Materials and Methods: 20 subjects diagnosed with chronic periodontitis were recruited to participate in split-mouth design and provided informed consent. Subgingival plaque sampling and clinical recording at baseline, 15 days and 1 month was performed. The patients received scaling and root planing, followed by Propolis administration subgingivally in the test sites. Significant differences between test and control were evaluated using the Mann-Whitney U test and Wilcoxon rank test.

Study Timeline

• Study Start: 2012-12
• Primary Completion: 2013-08
• Status Verified: 2013-09
• Study First Submitted: 2013-09-02
• Study First Submitted QC: 2013-09-16
• Last Update Submitted: 2013-09-16
• Study First Posted: 2013-09-17
• Last Update Posted: 2013-09-17
• Study Completion: 2013-10

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• good general health
• chronic periodontitis
• minimum of 20 natural teeth with at least one pocket per quadrant
• probing depth (PD) between 5 and 8 mm.

Exclusion Criteria

• subgingival instrumentation within 3 months
• antibiotic therapy within 3 months prior to the start of the study;
• smokers
• pregnant or nursing women
• intolerance or allergy to honey products

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Propolis	scaling root planing	-
scaling and root planing	scaling root planing	-
Propolis	Propolis	-

Primary Outcome Measures

Name	Time	Method
Change in the probing pocket depth and clinical attachment level	three time points of baseline,2 weeks, 4 weeks

Secondary Outcome Measures

Name	Time	Method
change in gingival index and microbiological changes	three time points baseline, 2 weeks, 4 weeks.

Trial Locations

Locations (1)

Rajarajeswari Dental College and Hospital; 🇮🇳 Bangalore, Karnataka, India