The comparative study of intravenous Ondansetron and Dexamethasone effects on reducing the incidence of postspinal anesthesia hypotension in elderly patients undergoing urologic surgeries

Phase 3

• Conditions: Condition 1: Post spinal hypotension in elderly patients. Condition 2: Post Spinal Bradycardia.; Bradycardia, unspecified; Hypotension; R00.1

• Registration Number: IRCT20230513058164N1
• Lead Sponsor: Yasouj University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

65 years of age or more
American Society of Anesthesiologists (ASA) physical status
EF>40%
Patients who do not have a contraindication for spinal anesthesia (such as coagulation disorder, thrombocytopenia )
Not allergic to local anesthetic No allergy to ondansetron or dexamethasone
Not taking drugs related to steroids or serotonin (for example, selective serotonin reuptake inhibitors)
Not suffering from uncontrolled cardiovascular, kidney, liver and thyroid diseases

Exclusion Criteria

Study Confounding Items Such as: Occurrence of Surgical Complications Such as Bleeding
Hemodynamic Instability

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Systolic Blood Pressure. Timepoint: 5 minutes before and 30 minutes following Spinal Anesthesia . Method of measurement: Sphygmomanometer.;Diastolic Blood Pressure. Timepoint: 5 minutes before and 30 minutes following Spinal Anesthesia. Method of measurement: Sphygmomanometer.;Heart Rate. Timepoint: 5 minutes before and 30 minutes following Spinal Anesthesia Procedure. Method of measurement: Pulse Oximeter.