Administration of ketamine into spinal Anaesthesia to prevent post amputation perception of pain in a limb that is no longer there.
Phase 1
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/10/058385
- Lead Sponsor
- Kathija Begam A
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patient undergoing elective lower extremity amputation under Subarachnoid Block
2. Age between 18-65 years old
3. American Society of Anaesthesiologists (ASA) I & II
Exclusion Criteria
1.Patients known allergic to either of the study drugs [Bupivacaine or Ketamine].
2.Patients with neuro-behavioural changes, severe diabetic /autonomic neuropathy.
3.Patients on long term analgesic medications and contraindicated for subarachnoid block.
4. Patients who failed follow ups for pain evaluation.
5. Patients who undergo further amputation during the follow up period are excluded from the further analysis.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Post operatively patient is developing the perception of pain or discomfort in a limb that is no longer there.Timepoint: from 6 hours to 6 months postoperatively
- Secondary Outcome Measures
Name Time Method To assess the incidence and severity of post amputation phantom limb pain.Timepoint: from 6 hours to 6 months postoperatively