NCT07197957招募中不适用
Clinical Utility of Cystatin C in the Early Detection of Contrast Induced Acute Kidney Injury
BayCare Health System4 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2025年3月11日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 100
- 试验地点
- 4
- 主要终点
- Incidence of AKI when sCr is used compared to when sCyC is used 24-48 hours after contract media and at 7-10 days follow-up
研究概览
简要总结
To determine the clinical utility of serum cystatin C in early detection of acute kidney injury (AKI).
详细描述
The primary objective of this study is to evaluate the clinical utility of Cystatin C in early detection of contrast-induced AKI.
To evaluate the effect of patient characteristics in the Cystatin C based GFR estimation in comparison to Cr based estimation.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subjects ages 18 years and above
- •Inpatients with CKD (Figure 1)
- •Order for CT imaging study or coronary angiography with isohexol Omnipaque) contrast media.
- •Pre and post contrast available
- •All races and ethnicity of patients are eligible. We expect to analyze approximately equal number of men and women in this study.
排除标准
- •Preexisting dialysis
- •Patients under the age of 18 years
- •Pregnancy
- •Incarcerated individuals
- •Patients with impaired cognition and unable to follow consent procedures
- •Recent exposure to CM (within 2 days before/after procedure)
- •Cardiac shock
- •Medications that affect biomarkers, including corticosteroids, lfamethoxazoletrimethoprim
结局指标
主要结局
Incidence of AKI when sCr is used compared to when sCyC is used 24-48 hours after contract media and at 7-10 days follow-up
时间窗: 10 days
次要结局
- Change from baseline in eGFRcr compared to change from baseline in eGFRcys 24-48 hours after contrast media and at 7 to 10 days follow-up(10 days)
研究者
研究点 (4)
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