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临床试验/NCT07022028
NCT07022028已完成不适用

Ventilator Weaning Practices in Patients Intubated for Guillain-Barré Syndrome or Myasthenia Gravis

Poitiers University Hospital1 个研究点 分布在 1 个国家目标入组 800 人开始时间: 2024年2月27日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
800
试验地点
1
主要终点
The proportion of patients with prolonged weaning

研究概览

简要总结

Guillain-Barré syndrome and myasthenia gravis are two neuromuscular diseases that are commonly managed in ICUs that may require different weaning protocols. To date, no study has compared weaning modalities from mechanical ventilation in patients with these two diseases. Our objective was to assess and compare for ventilator weaning modalities between patients mechanically ventilated for Guillain-Barré syndrome or for myasthenia gravis in a large-scale multicenter study.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

性别
All
接受健康志愿者

入选标准

  • All patients mechanically ventilated for at least 48 hours for Guillain-Barré syndrome or myasthenia gravis -

排除标准

  • Patients mechanically ventilated less than 48h or intubated for another reason than the neuromuscular disease.

结局指标

主要结局

The proportion of patients with prolonged weaning

时间窗: 7 days after the initial separation attempt from the ventilator

Prolonged weaning defined as still being under mechanical ventilation at least 7 days after the initial separation attempt from the ventilator

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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