Metabolic profile in boys, adolescents and men with Klinefelter syndrome (47,XXY) and variants - cross-sectional cohort study (comparison to population-based data)
Recruiting
- Conditions
- Q98.1Klinefelter syndrome (47,XXY and variants)Klinefelter syndrome, male with more than two X chromosomes
- Registration Number
- DRKS00034760
- Lead Sponsor
- Klinik für Kinder- und Jugendmedizin, St. Josef-Hospital Bochum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Male
- Target Recruitment
- 40
Inclusion Criteria
Confirmed diagnosis of Klinefelter syndrome
- Signed consent (for underage participants consent by the legal guardian)
Exclusion Criteria
- Revocation of the patient's consent/lack of consent
- Lack of language skills
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Prevalence of metabolic syndrome by analysing fasting whole blood sample, physical examination + urine test (one study appointment required)
- Secondary Outcome Measures
Name Time Method - Body composition by body impedance measurement using BIA scales<br>- Insulin resistance (blood sample analysis)<br>- Inflammation parameters (blood sample analysis)