Prediction of TAPSE/PASP Ratio for Hypotension Due to General Anesthesia Induction in Pulmonary Resection Surgery
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 52
- Locations
- 1
- Primary Endpoint
- echocardiography
Study Overview
Brief Summary
TAPSE, one of the methods for evaluating right ventricular systolic function; It is a bar parameter that can easily measure apex-basal shortening and provides specific information about global RV function. TAPSE/PASP can be calculated as load-independent parameters to evaluate RV function. Because RV function is sensitive to change in afterload, known as the RV-pulmonary circulation (PC) connection.
This study aims to identify patients who are candidates for hypotensive events due to general anesthesia in a hemodynamically stable population.
Detailed Description
TAPSE, one of the methods for evaluating right ventricular systolic function; It is a bar parameter that can easily measure apex-basal shortening and provides specific information about global RV function. TAPSE/PASP can be calculated as load-independent parameters to evaluate RV function. Because RV function is sensitive to change in afterload, known as the RV-pulmonary circulation (PC) connection.
This study aims to identify patients who are candidates for hypotensive events due to general anesthesia in a hemodynamically stable population.
Patients will be measured by transthoracic echocardiography in the preoperative period, 15-30 minutes before induction.
Basal hemodynamic parameters and non-invasive and/or hemodynamic values will be recorded every two minutes after induction until surgical incision.Patients with a 30% decrease in SBP from the baseline and a decrease in MAP below 65 mmHg in the first 10 minutes after anesthesia induction will be considered to have hypotension. Patients will be divided into 2 groups: 'with' and 'without' hypotension.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to 75 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Written informed consent;
- •18-75 years old
- •ASA Physical Status 1-3;
- •Patients planned for pulmonary resection surgery
Exclusion Criteria
- •The patient is pregnant
- •After cardiac surgery
- •Severe pulmonary hypertension
- •Severe valve disease
- •Hypertrophic or dilated cardiomyopathy
- •Presence of acute myocardial infarction
- •Patients with severe visual or hearing impairment/disability
- •ASA physical status IV or V
- •Ischemic heart disease, conduction disorder.
- •History of long-term use of certain medications (β-blockers, angiotensin converting enzyme inhibitors, analgesics, sedatives or tricyclic antidepressants)
Outcomes
Primary Outcomes
echocardiography
Time Frame: 30 minute
TAPSE/ PASP (mm/mmHg)
Secondary Outcomes
- tension(4-5 hours)
Investigators
ferdi gülaştı
Assistant prof.dr.
Aydin Adnan Menderes University