Prediction of TAPSE/PASP Ratio for Hypotension Due to General Anesthesia Induction
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 52
- 试验地点
- 1
- 主要终点
- 1. tension
研究概览
简要总结
TAPSE, one of the methods for evaluating right ventricular systolic function; It is a bar parameter that can easily measure apex-basal shortening and provides specific information about global RV function. TAPSE/PASP can be calculated as load-independent parameters to evaluate RV function. Because RV function is sensitive to change in afterload, known as the RV-pulmonary circulation (PC) connection.
This study aims to identify patients who are candidates for hypotensive events due to general anesthesia in a hemodynamically stable population.
详细描述
TAPSE, one of the methods for evaluating right ventricular systolic function; It is a bar parameter that can easily measure apex-basal shortening and provides specific information about global RV function. TAPSE/PASP can be calculated as load-independent parameters to evaluate RV function. Because RV function is sensitive to change in afterload, known as the RV-pulmonary circulation (PC) connection.
This study aims to identify patients who are candidates for hypotensive events due to general anesthesia in a hemodynamically stable population.
Patients will be measured by transthoracic echocardiography in the preoperative period, 15-30 minutes before induction.
Basal hemodynamic parameters and non-invasive and/or hemodynamic values will be recorded every two minutes after induction until surgical incision.Patients with a 30% decrease in SBP from the baseline and a decrease in MAP below 65 mmHg in the first 10 minutes after anesthesia induction will be considered to have hypotension. Patients will be divided into 2 groups: 'with' and 'without' hypotension.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Written informed consent;
- •18-75 years old
- •ASA Physical Status 1-3;
- •Patients planned for surgery
排除标准
- •The patient is pregnant
- •After cardiac surgery
- •Severe pulmonary hypertension
- •Severe valve disease
- •Hypertrophic or dilated cardiomyopathy
- •Presence of acute myocardial infarction
- •Patients with severe visual or hearing impairment/disability
- •ASA physical status IV or V
- •Ischemic heart disease, conduction disorder.
结局指标
主要结局
1. tension
时间窗: 4-5 hours]
Intraoperative systolic arterial tension, diastolic arterial tension and mean arterial tension will be taken and recorded for the patients.
次要结局
未报告次要终点
研究者
ferdi gülaştı
ASS. PROF. DR
Aydin Adnan Menderes University