Supported rescue packs (medications and instructions) post-discharge in chronic obstructive pulmonary disease
Not Applicable
- Conditions
- Chronic obstructive pulmonary disease (COPD)Respiratory
- Registration Number
- ISRCTN44283921
- Lead Sponsor
- King's College London
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Ongoing
- Sex
- All
- Target Recruitment
- 1400
Inclusion Criteria
1.Adults aged 40 years and over
2.Patient to be discharged from hospital with exacerbation of COPD
3.Able to provide informed consent
Exclusion Criteria
1.Requirement for invasive ventilation during the hospital admission
2.Patients who have an expected survival of less than 90 days
3.Discharge to residential or nursing home
4.Inability to engage with supported self-management
5.No access to telephone.
6.Participation in another intervention study
7.Individuals discharged from hospital to a non-physical virtual ward
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Time to first all-cause readmission within 90 days of discharge measured using patient records
- Secondary Outcome Measures
Name Time Method Measured using patient records:<br>1.Time to and frequency of COPD-related readmissions at 30 and 90 days<br>2.Days alive and out of hospital at day 90<br>3.Time to and frequency of all COPD exacerbations at days 30 and 90<br>4.Cumulative systemic oral corticosteroids use over 90 days<br>5.Cumulative systemic antibiotic use over 90 days<br>6.Health care contacts at baseline, days 90 and 180, and 1 year<br>7.All cause readmission at 30 days<br>8.All cause-, cardiovascular- and COPD- related mortality at day 90 and over 12 months<br>9.Quality of life (COPD assessment Test (CAT) score and EQ-5D-5L) at baseline , days 90 and 180, and 1 year<br>10.Incremental cost-effectiveness ratio (ICER, a ratio of the additional cost divided by the additional effectiveness of SRP compared to UC) at days 90 and 180 and 1 year<br>11.Qualitative description of usual care<br>12.Qualitative examination of fidelity to and adaptation of the plan in the intervention arm<br>13.Adverse events<br>14.Antimicrobial resistance<br><br>