The Impact of Branched Chain Amino Acids (BCAA) Supplementation in Patients with Advanced Liver Disease

Phase 2

Completed

• Conditions: Cirrhosis; Sarcopenia; Malnutrition; Hepatic encephalopathy; Infections; Insulin resistance; Immune function; Oral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon; Diet and Nutrition - Other diet and nutrition disorders; Infection - Studies of infection and infectious agents

• Registration Number: ACTRN12618000802202
• Lead Sponsor: Austin Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-05-11
• Study Completion: 2022-06-07
• Last Update Posted: 18 July 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

Adult patients who meet the following criteria will be invited to participate
1. Cirrhosis with a radiological, clinical or histological diagnosis
2. A low serum albumin or the presence of ascites
3. Muscle weakness as determined by hand dynamometer

Exclusion Criteria

-Patients > 75 and < 18 years of age
-Prognosis or time to transplant < 6 months as determined by the treating clinician
-Active heavy alcohol intake
-Advanced hepatocellular carcinoma
- Lactose intolerance

Study & Design

• Study Type: Interventional
• Study Design: Not specified